Both Restylane and Juvederm are frequently mentioned in fashion magazines and the lay press as fillers which can effectively soften folds and wrinkles. Many people are asking about the differences in the two. Restylane and Juvederm are both hyaluronic acid products. Hyaluronic acid is a naturally occurring substance in the body. Restylane and Juvederm are very similar in composition but there are importance differences which have made Juvederm the treatment of choice for many plastic surgeons. Juvederm is somewhat more concentrated and is more "cross-linked" which produces a smoother result. Proponents of Juvederm point out that these differences have distinct advantages including less bruising, milder pinkness and decreased swelling following the injection. Most patients report less discomfort both during and after the injection of Juvederm and a longer lasting result. Additionally, it appears that a smaller volume of Juvederm is required to achieve the same results.