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In 2002 the FDA approved the use of BOTOX®  Injections for cosmetic purposes, specifically for the treatment of lines and furrows between the brows.  BOTOX®  Cosmetic is now widely used to reduce the appearance of facial lines and wrinkles. BOTOX®  is also an accepted treatment for underarm sweating, muscle spasticity, and debilitating headaches. How Does BOTOX®  Cosmetic Work? Unlike dermal fillers, which literally "fill in" fine lines and wrinkles, BOTOX®  injections target the muscles that are responsible for creating facial wrinkles. Specifically, BOTOX®  injections reduce the movements of these active facial muscles, gradually eliminating existing lines and wrinkles and preventing the formation of new wrinkles. BOTOX®  Cosmetic is particularly effective for eliminating wrinkling and furrows between the brows. As part of the treatment process, your physician will observe which facial muscles are causing wrinkles to form and will inject the BOTOX®  solution directly into those mus